NATURAL COLLAGEN Q5-28

The abilities of this product to being absorbed can shock clinicists. 30 minutes after application on epidermis - collagen starts implementing itself into proper skin cells. About 48 hours later, one can state a significant ...

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KNOWLEDGE FOR THE ADVANCED

Rarely does a good presentation of a product require the usage of information presented below, with the exception of coming across a chemistry, biology or medicine specialist. An average buyer does not know the majority of professional terminology and they might perceive spontaneous usage of such words as mouthing off and treat it with animosity.
Things can look totally different, when our interlocutor shows interest and inquisitiveness. A Natural Collagen Distributor has to know the answers to absolutely every question directed at him. Therefore it is o bligatory for everybody to acquire this knowledge; for everybody who wants to treat this business professionally.

Colla - glue, genno - to give birth. These Greek words depict the functioning of collagen. It is a protein joining cellular elements, which makes it possible for them to create tissues and organs. During all the life of an organism, collagen remains in constant exchange. The most enduring is located in bones, where the exchange takes place every year, the least lasting - in the liver, where it takes place on a monthly basis.

Collagen is a simple protein, made exclusively of amino acids, which belong to fibrous proteins, to put it strictly - to fibrous scleroproteins. It is made of long, spiral peptide chains of 19 amino acids. The most important of them are: proline, glycine. hydroxyproline and hydroxylizyne, while the two later ones do not practically appear in other proteins.

Amino acids are made of carbon, oxygen and hydrogen, which react with the atoms of nitrogen. When at least a hundred of amino acids have joined together, they create a poly-peptide chain. That is the way a protein is born. That is also the way collagen is created.

When it comes to collagen, thanks to its chain structure, amino acids create a spatial spiral, called super helix.

One of the crucial features of a collagen super helix is die sequence of three amino radicals, according lo formula: _X_Y_Z, where Y and Z radicals are built into polypeptide chain. Protein chain spiral is supported by weak hydrogen bonds. These bonds in naturally occurring collagen may be broken in the period of sickness. That is one of the reasons why a person dies, when their body temperature exceeds 42°C. That is also the same reason why collagen obtained out of freshwater fish gets despiralised in the temperature higher than in their natural surroundings.

Protein
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	Collagen particles ordered in triple helix
	Collagen particles after the dissolution of spatial structure

Rarely does a good presentation of a product require the usage of information presented below, with Collagen being an element of our skin is arranged just like in the upper picture. None of the collagens used in world cosmetology as implants and cr?me ingredients keep the triple helix.

That is why the Polish invention is so ingenious.

The dissolution of the triple helix in collagen obtained from fish happens extremely easily. The presence of acid reaction (caused by e.g. bacterium appearance) or major increase in body temperature might make its particles despiralise.
Collagen loses its biological activity and the ability to join twin particles in the skin. It slowly gets denaturated, and coagulates. It ceases to be a youth potion, and becomes an ordinary moisturizing gel.
As regards collagen absorbing, American [E. Gibson, L. Chang 2002] and French [J. Roche 2003] researches, apart from acid and temperature, mention also time, as factors having the influence on the process.

It has to be said that even the best absorbable product, made by INVENTIA POLISH TECHNOLOGIES keeps the spatial collagen structure only up o 23,8°C and it seems to be the limit of biotechnology achievements.
The temperature of human body - about 37°C despiralises collagen from an easily absorbable gel just after 50-55 minutes.
If you want lo say that you have a youth potion, it is not enough to obtain collagen from fish skin and emulate it to the shape of gel, as other companies say.
A product with objective skin repairing powers, according to clinics, should fulfill a line of conditions. Apart from the aforementioned ones, it should be produced from a protein with its tropocollagen molecular mass significantly higher than 310 000, which is the feature of collagen found in human skin tissue [G. Reich 1970].

INVENTIA POLISH TECHNOLOGIES collagen is obtained with its molecular mass of 250 000 - 310 000, which enables it to enter skin and to start in building into tissues, in a time much shorter than the despiralising risk point, without it losing the triple helix.
None of the other collagen producers in the world has been awarded a positive opinion by the biochemistry, biotechnology and medicine specialists as regards the above problem.

In order to understand better the revolution in cosmetology that we are now beginning, one has to know that:
Collagen and elastin are skin supporting proteins, which ensure its tone, moistening, elasticity and firmness.
From the age of 25 years, human skin starts slowly to lose these features, just like the muscles lose strength, and the bones - calcium. All these signs of getting old are the result of dissolvable collagen deficit, the biosynthesis of which gets weaker with the passage of time.
After the 30 th year of age, practically in every person, degeneration of sebaceous and sudoriferous glands, progressing skin dryness and flubbing can be observed. Wrinkles start appearing. The reason of these changes is the weakening of elastin and collagen fibers. Free radicals, toxins and an enzyme called collagenase destroy protein fibers, and the level of microelements and vitamins - stimulating natural production of collagen - in the organism decreases.
Collagen rotation within the body still continues, but the older the body gets, the more often a process of degradation occurs, in comparison to the process of synthesis. It regards especially dissolvable collagen synthesis, which used to make the skin elastic, thanks to the ability of water bonding.

Natural Collagen Formula 5-26 is a water solution of collagen and elastin, with an additive of ethyl-, methyl-, propylparaben - as a natural preservative (cranberry extract) and lactic acid. The fact that the producer decided not to use any colouring and fragrance is not caused by ecologically friendly attitude, but it is caused by the concern lo protect the triple helix. Lactic acid is the only acid reaction, which does not endanger fibre spatial structure, but acting keratolically accelerates epidermis exfoliation and spots brightening.
By loosening comeocytes, it allows the fish fibryles, hidden in Omega 3 and Omega 6 fatty acid particles, to reach twin fibers in the skin, before the body temperature endangers their spiral structure.

Natural Collagen Formula 5-22 and finally 5-26 has always been produced in sterile conditions -comparable to those in laboratories - by qualified chemists. Water used in the production process undergoes hyper filtration by reverse osmosis, while the vessels and tools undergo sterilization. Preparations are placed in glass containers with a batcher mechanism and are protected against overheating by special isolation of the package. All this is done with one aim in mind: to protect collagen's spatial structure, which is a deciding factor when it comes to its effectiveness.
Absorbable gel offered by COLWAY, after entering the skin creates a protein net, which makes up scaffolding for new collagen produced by fibroblasts. This net binds water and lipofil substances. Researches on human skin tissues have confirmed an increased production of collagen by fibroblasts, epidermis thickening, and increase in the amount of mucin and sluice substances in the papillary layer of skin.
The abilities of this product to being absorbed can shock clinicists. 30 minutes after application on epidermis - collagen starts implementing itself into proper skin cells. About 48 hours later, one can state a significant increase in the level of hydroxyproline around chondrocytes producing collagen in the bones.
These are objective test results, obtained in various centers, correlating with each other. Natural Collagen has also received very positive opinions in beauty salons, hairdresser's, biological regeneration centers, but predominantly in consumer questionnaires.

That's more or less all about the role of this wonder product in cosmetics.

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What goes beyond that is medicine . It has been proven that fish collagen has got a beneficial influence when it comes to treatments of paradonthosis, skin allergies, acne, dandruff, psoriasis, burns, dermatosis, pattern balding, oedema, joints inflammation and many other ailments.

The product softens scar edges, speeds up a process of wound, abrasion and irriation cicatrizing. It is extolled in the fight against cellulite and strechmarks. It heals stings wonderfully. It eliminates freckles, stops the growth of grey hair, regenerates hair and nails. Applied on eyelids improves the eyesight. It is used as a treatment against aphtae, herpes, stye, felon, and abscess. Collagen slows down the process of sebaceous and sudoriferous glands atrophy. It heals heel spurs, eliminates rips and solves the problem of cuticle delay ring around nails. Every day we learn about some new implementations of the product, e.g. in horses treatments before auctions, or in organ transplantology - mainly in transport and preservation. We stopped wondering, having finally understood, that collagen constitutes 30 % of protein mass in our body, and for example, in the skin or eye - 70%.

Fish collagen will definitely eliminate bovine collagen from implantology, and from first-aid dressing industry, from vascular prostheses and surgical stitches. Clinical researches seem to be very promising as regards treatment against osteoporosis and rheumatism. Actually, we can already speak about success, at least in preservative treatment of these ailments.

Polish fish collagen is waiting to being registered by the Commission for Medicine Acceptance.
There haven't been any clinically proven contraindications. People allergic to fish protein do not constitute even a per mill of population. Until the test have been finished we can speculate that among contraindications we can find: chemotherapy, collagenosis skin disorders, low-protein diet in severe kidney inefficiency. Because of purely legal reasons collagen should not be advised to pregnant women, which can be difficult to achieve, as its effectiveness in eliminating strechmarks is widely known.

Collagen in action - skin (section)